INTRODUCTION In a general fermentation process, occurring in a fermenter, there is a contact between micro-organisms and feed solutions to the bioreactor parts. Before going further to the next batch these fermenters need to be properly cleaned, sterilized and free of in process residues and endotoxins. A hygienic and cleaning environment is necessary for microbial growth in large production plants. Manual cleaning of fermenter parts is not easy procedure, an automated cleani